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Journal: Virology Journal
Article Title: Evaluation of three alternative methods to the plaque reduction neutralizing assay for measuring neutralizing antibodies to dengue virus serotype 2
doi: 10.1186/s12985-024-02459-y
Figure Lengend Snippet: Comparison of DENV-2 neutralization titers obtained by the MTT-based microneutralization, the xCELLigence RTCA and the iPA-FRNT assays with the standard PRNT assay. Linear regression and scatterplot of neutralizing titers comparing the evaluated assay with standard PRNT at neutralization endpoints of 50% (left panel), 70% (middle panel) and 90% (right panel). Panel A-C : MTT-based microneutralization assay. Non-linearity was observed for two of three neutralization endpoints (NT 70 and NT 90 ). ( D-F ) xCELLigence RTCA assay. ( G-I ) iPA-FRNT assay. At all three neutralization endpoints, positive correlation was observed for both the xCELLigence RTCA and iPA-FRNT assays
Article Snippet: The
Techniques: Comparison, Neutralization, Plaque Reduction Neutralization Test, Microneutralization Assay
Journal: Virology Journal
Article Title: Evaluation of three alternative methods to the plaque reduction neutralizing assay for measuring neutralizing antibodies to dengue virus serotype 2
doi: 10.1186/s12985-024-02459-y
Figure Lengend Snippet: Comparison of alternative methods to the plaque reduction neutralizing assay for measuring neutralizing antibodies to DENV-2
Article Snippet: The
Techniques: Comparison, Neutralizing Assay, Virus, Cell Culture